Left ventricular and atrial segmentation of 2D
echocardiography with convolutional neural networks

2020 SPIE-Medical Imaging

Abstract: Segmentation of heart substructures in 2D echocardiography images is an important step in diagnosis and management of cardiovascular disease. Given the ubiquity of echocardiography in routine cardiology practice, the time–consuming nature of manual segmentation, and the high degree of inter-observer variability, fully automatic segmentation is a goal common to both clinicians and researchers. The recent publication of the annotated CAMUS dataset will help catalyze these efforts. In this work we develop and validate against this dataset a deep fully convolutional neural network architecture for the multi-structure segmentation of echocardiography, including the left ventricular endocardium and epicardium, and the left atrium. In ten-fold cross validation with data augmentation, we obtain mean Dice overlaps of 0.93, 0.95, and 0.89 on the three structures respectively, representing state of the art on this dataset. We further report small biases and narrow limits of agreement between the automatic and manual segmentations in derived clinical indices, including median absolute errors for left ventricular diastolic (7.3mL) and systolic volumes (4.9mL), and ejection fraction (3.8%), within previously reported inter-observer variability. These encouraging results must still be validated against large-scale independent clinical data.

Paper (pdf, preprint)
Slides from the talk

The below animation shows our segmentation results over all time phases for an example apical four chamber echo from the CAMUS datasaet.

Left ventricle and atrial segmentation for four chamber echocardiography